Alternating hemiplegia of childhood

A rare syndrome characterized by episodes of HEMIPLEGIA or QUADRIPLEGIA that can last from minutes to days. Most cases are accompanied by DYSTONIA, choreoathetoid movements, nystagmus, other ocular motor abnormalities, autonomic disturbances, and progressive cognitive impairment. It may mimic or overlap with other disorders, such as FAMILIAL HEMIPLEGIC MIGRAINE and GLUT1 deficiency syndrome. Germline mutations in the ATP1A2 gene have been identified. OMIM: 104290

Also Known As:

Alternating hemiplegia; Alternating hemiplegia syndrome

Nervous System Diseases: 14737
- Neurologic Manifestations: 7223
  - Paralysis: 14443
    - Hemiplegia: 1630
      - Alternating hemiplegia of childhood: 107
Signs and Symptoms Pathological Conditions
- Signs and Symptoms
  - Neurologic Manifestations: 7223
    - Paralysis: 14443
      - Hemiplegia: 1630
        Alternating hemiplegia of childhood: 107

ATP1A3 Working Group Selected Research

ATP1A3 Working Group Research Topics

Disease

Drug/Important Bio-Agent (IBA)